Severe Asthma Research Program (SARP)
A National Institutes of Health/ National Heart, Lung & Blood Institutes
Why does asthma become more common in women with age? Why do boys tend to "outgrow" their asthma, but not girls? We think that the answers to these questions are important for asthma management. We have new clues to the answers, and aim to solve these mysteries. Men and women are examples of distinct asthma "subpopulations" that can have distinct mechanisms underlying their asthma symptoms. We believe we have identified a number of asthma subpopulations with specific, causative chemical or hormonal inbalances that may contribute to asthma symptoms. The goal of our project is to be sure we can correctly diagnose these underlying issues in specific subpopulations. P roper diagnosis will enable the development of effective management strategies to target the right medicines, nutrition and lifestyle changes to the right patients.