Severe Asthma Research Program    (SARP)
A National Institutes of Health/ National Heart, Lung & Blood Institutes
sponsored network

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Washington University St. Louis                 Information for Asthmatics and caregivers
PARTICIPATE IN SARP - Washington University St. Louis

Our goal is to better understand the changes that occur in the airways of people with severe asthma and what happens to these airways over time.  We will be studying adults and children with severe asthma using CT and MRI imaging, along with other measurements of the airways. We will compare what we find with other study subjects that have well- controlled asthma, no airway disease, and people with chronic bronchitis. By studying these changes we hope to identify people with asthma that would benefit from specific targeted therapy. This project will lead to new insights on the mechanistic basis for severe asthma, how it differs from mild-moderate asthma, identify new targets for intervention, and will provide imaging measurements to evaluate outcomes for new asthma treatments.

The Washington University in St. Louis site will include a site for adult participants at Washington University Medical Center (Division of Pulmonary, Allergy and Critical Care Medicine) and a site for children in the division of Pulmonary Medicine, Allergy, and Immunology at St. Louis Children’s Hospital.

Site Investigators and Locations:



 
Mario Castro, MD; Principal Investigator
Washington University
St. Louis, Missouri 63110 
 
Leonard Bacharier, MD; Co-Investigator
Washington University
St. Louis, Missouri 63110 

David Gierada, MD; Co-Investigator
Washington University
St. Louis, Missouri 63110 

Kenneth Schechtman, PhD; Co-Investigator
Washington University
St. Louis, Missouri 63110 

Jason Woods, PhD; Co-Investigator
Washington University
St. Louis, Missouri 63110 

Site Coordinator Contact:

Becky Schutz    
Phone: 314-362-8892    
Email: rschutz@dom.wustl.edu


Interested in Participating in SARP?

You will likely qualify for participation in SARP as a severe asthmatic if you: 
1.    Have been diagnosed with asthma by a physician
2.    Require high  or continuous doses of asthma medications, such as Advair, Symbicort, prednisone or medrol 
3.    Still have asthma symptoms on a regular basis 
4.    Have had frequent or severe exacerbations of asthma (requiring prednisone,  ER visits, hospitalizations)
5.    Are not currently smoking and have smoked less than 5-10 years total
6.    Are between the ages of 6 yrs and 75 yrs of age

You may also qualify for participation in SARP as a “comparative” patient with mild asthma.     Similarly, you must be diagnosed with asthma, be between 6 and 75 yrs of age and not be currently smoking or have smoked for more than 5-10 yrs

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